Abstract
Low energy laser irrad´imion(LELI) therapy in physical therapy is widespread but the mechanisms are not fully, understood. The purpose of the present study was to examine the epidermal growth factor(EGF)´ s expression within lumbar spinal cord which corresponding with crushed extensor digitorum longus(EDL) of rats -after-- low-energy laser irradiation applied. After a crushed injury on the right EDL, low-energy laser irradiation was applied by using 2000mW, 2000Hz, 830nm GaAIAs(Gallium-aluminum-arsenide) semiconductor diode laser. The laser treatment was performed with 10 minutes daily for 3days.
After EDL crush injury, EGF immunoreactive positive neurons in experimental group were progressively decreased from the first to third days. Especially I day subgroup is highly expressed in dorsal horn(Lamina 1, Ii, 111) and around of central canal of spinal cord(Lamina V11). Control group was only expressed slightly at 3 days.
This study suggests that LELI stimulate that release and migration of EGF in spinal cord, which district to .r wound site, therefore promote wound healing of EDL crush injury.
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